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CELL BIOTECH LAB2PRO™

以微生物科學促進人類健康 開拓創新益生菌解決方案

Microbiome Science For Human Health
Pioneering Innovative Probiotic Solutions

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傑出學術成就

89專利
0 專利
107論文發表
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30臨床實驗
0 臨床實驗
7全基因組測序論文
0 全基因組
測序論文
  • GMP、HACCP、HALAL、KOSHER
    產品認證

  • 300多名微生物專家組成,
    專注於研究益生菌乳酸菌的團隊

  • 唯一針對亞洲圈飲食,對於含有薑、蒜、葱、辣椒等强烈辛香料飲食,
    可抵抗防止被滅殺的益生菌

  • 獲選Forbes(富比士)亞洲最具前景企業200強、亞洲最佳中小企業200強

  • 國際學術大會及定期學術大會上榮獲「技術獎」(韓國微生物生命工學會)

  • 被評為「World Class 300」(中小企業廳,產業通商資源部)

  • 通過人體臨床試驗在KCTC及德國菌株銀行(DSMZ)註冊,具可靠性及安全性

HALAL HACCP,FDA

LAB2PRO™
雙層複合基質包埋保護專利

益生菌存活率提高10倍*

(模擬腸道環境中與未包埋益生菌相比)
*資料來源:Archives of Pharmacal Research, July 2015, Volume 38, Issue 1, p1345-1350

LAB2PRO™ LAB2PRO™

1層包埋:胜肽/蛋白質基底

1st coating layer:
peptide / protein matrix

2層包埋:親水膠體多醣基質

2nd coating layer:
hydrocolloidal polysaccharide matrix

包埋技術與益生菌存活率的關係

存活率(%)
0% Oxgall(非腸道環境) 1% Oxgall(模擬腸道環境)
存活率
10
5.60%
無包埋
Non Coated
55.20%
有包埋
Dual Coated
100
80
60
40
20
0

五國專利 雙層複合基質包埋保護專利

包埋技術與益生菌存活率的關係
智慧定點釋放

智慧
定位
酸鹼值依存脫包埋釋放系統 HUMAN pH-DEPENDENT RELEASE SYSTEM

pH 2.0(胃)

pH 4.0(十二指腸)

pH 7.0(小腸)

pH 2.0(胃)->pH 4.0(十二指腸)->pH 7.0(小腸)
雙層包埋保護胜肽/蛋白質基底及親水膠體多醣基質儘管暴露於pH2.0-4.0,包埋仍保持完整。
十二指腸和空腸中,膽汁膽鹽和腸液將pH值提高到6左右,從而將益生菌從包埋層中漸漸釋放出來。
在迴腸和結腸中的pH值為7.0時包埋層完全溶解,使得益生菌能夠定殖和增殖於小腸中。
pH 2.0(胃)->pH 4.0(十二指腸)->pH 7.0(小腸)

pH 2.0(胃)

雙層包埋保護胜肽/蛋白質基底及親水膠體多醣基質儘管暴露於pH2.0-4.0,包埋仍保持完整。

pH 4.0(十二指腸)

十二指腸和空腸中,膽汁膽鹽和腸液將pH值提高到6左右,從而將益生菌從包埋層中漸漸釋放出來。

pH 7.0(小腸)

在迴腸和結腸中的pH值為7.0時包埋層完全溶解,使得益生菌能夠定殖和增殖於小腸中。

pH 2.0(胃)

雙層包埋仍保持完整

ph2.0

pH 6.0(十二指腸和空腸)

益生菌從包埋層中漸漸釋放出來

ph6.0

pH 7.0(小腸)

包埋層完全溶解

ph7.0

pH 7.0(小腸)

益生菌能夠定殖和增殖於小腸

ph7.0
通過辛香料測試

也許您不怕辣也愛吃辣,
但可曾想過您吃的益生菌無法抵抗辛香料的殺菌效果?

來自韓國的正宗血統
LAB2PRO™不怕辣~!

不同辛香料對於有(無)包埋益生菌存活率的關係

  • CBT-A / CBT-G / CBT-Z / CBTC:不同之雙層複合基質包埋保護專利益生菌株
  • EP:無包埋歐洲菌株

蜂膠Propolis

不同辛香料對於有(無)包埋益生菌存活率的關係 - 蜂膠

Scallion

洋蔥Onion

不同辛香料對於有(無)包埋益生菌存活率的關係 - 蔥/洋蔥

大蒜Garlic

Ginger

不同辛香料對於有(無)包埋益生菌存活率的關係 - 大蒜/薑

青陽辣椒Chungyang red pepper

紅椒Red pepper

不同辛香料對於有(無)包埋益生菌存活率的關係 - 青陽辣椒/紅椒

益生菌的安全性
源自於完整的鑑定

LAB2PRO™的菌株通過驗證採用最新技術完成

全基因組序列中找尋特殊遺傳信息

Finding Special Genetic Information from the Full Genome Sequence

16S rRNA序列分析

16S rRNA Sequence Analysis

抗生素耐藥性測試

Antibiotic Resistance Test

毒理測試

Toxicity Assessment

生理功能評估

Physiological Function Test

確保菌株的安全性及專一性

每株益生菌菌株均獲得唯一的菌株編號,在韓國(KCTC)和德國(DSMZ)的授權機構中安全儲存和管理,同時在美國國家生物技術信息中心(NCBI) 註冊的DNA序列。

菌株保存

kcec Korean Collection for Type Cultures (KCTC)
dsmz Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ)

DNA序列註冊

ncbi U.S. National Center for Biotechnology Information (NCBI)

保證最高品質益生菌發酵優化技術 Probiotic Fermentation Optimization Technology that Guarantees the Highest Quality

LAB MANUFACTURING PROCESS

LAB2PRO™益生菌系列

益生菌菌屬
Genus (Cell Type)
菌株代號
Name
益生菌菌種
Species
來源
Origin
GRAS 特性
Characteristics
Lactobacillus CBT-LA1 Lactobacillus acidophilus Healthy Human O It has antibacterial activity against harmful bacteria such as E. coli, Salmonella and excretes LPS (Lipopolysaccharide) from body.
CBT-LC5 Lactobacillus casei Healthy Human It plays a role in maintaining intestinal immune balance. Especially, it is effective in inhibiting autoimmune diseases such as rheumatoid arthritis and atopic dermatitis.
CBT-LP3 Lactobacillus plantarum Fermented food O A representative lactic acid bacteria strain isolated from Kimchi. It is highly effective in degrading cholesterol.
CBT-LPC5 Lactobacillus paracasei Fermented food A strain to ferment the yogurt, enhances the richness of yogurt.
CBT-LR5 Lactobacillus rhamnosus Healthy Human O It is excellent for intestinal colonization and has anti-inflammatory effect controlling pro-inflammatory cytokine.
Bifidobacterium CBT-BT1 Bifidobacterium longum bv. infantis Healthy Baby O A strain degrades HMO (Human Milk Oligosaccharide) and synthesizes vitamin B group. Urea can be decomposed to help recycle nutrients in the intestines.
CBT-BL3 Bifidobacterium lactis Healthy Baby O It has anti-colitis effect and anti-inflammatory effect by regulating the role of pro-inflammatory cytokine in relation to intestinal immune balance.
CBT-BR3 Bifidobacterium breve Healthy Baby O In addition to HMO degradation function, it also has effects on metabolic syndrome and acetaldehyde decomposition function.
CBT-BF3 Bifidobacterium bifidum Healthy Baby O A strain degrades HMO and locates as the dominant species of intestinal flora within the first 1-2 weeks of life.
CBT-BG7 Bifidobacterium longum Healthy Baby O Degrading HMO, it also has high antiviral activity against rotavirus and inhibits the activity of H.pylori.
Coccus CBT-ST3 Streptococcus thermophilus Healthy Human O It grows rapidly in the intestine and helps Lactobacillus and Bifidobacterium settle in the intestines.
益生菌菌屬
Genus (Cell Type)
Lactobacillus
菌株代號
Name
益生菌菌種
Species
來源
Origin
GRAS 特性
Characteristics
CBT-LA1 Lactobacillus acidophilus Healthy Human O
It has antibacterial activity against harmful bacteria such as E. coli, Salmonella and excretes LPS (Lipopolysaccharide) from body.
CBT-LC5 Lactobacillus casei Healthy Human
It plays a role in maintaining intestinal immune balance. Especially, it is effective in inhibiting autoimmune diseases such as rheumatoid arthritis and atopic dermatitis.
CBT-LP3 Lactobacillus plantarum Fermented food O
A representative lactic acid bacteria strain isolated from Kimchi. It is highly effective in degrading cholesterol.
CBT-LPC5 Lactobacillus paracasei Fermented food
A strain to ferment the yogurt, enhances the richness of yogurt.
CBT-LR5 Lactobacillus rhamnosus Healthy Human O
It is excellent for intestinal colonization and has anti-inflammatory effect controlling pro-inflammatory cytokine.
益生菌菌屬
Genus (Cell Type)
Bifidobacterium
菌株代號
Name
益生菌菌種
Species
來源
Origin
GRAS 特性
Characteristics
CBT-BT1 Bifidobacterium longum bv. infantis Healthy Baby O
A strain degrades HMO (Human Milk Oligosaccharide) and synthesizes vitamin B group. Urea can be decomposed to help recycle nutrients in the intestines.
CBT-BL3 Bifidobacterium lactis Healthy Baby O
It has anti-colitis effect and anti-inflammatory effect by regulating the role of pro-inflammatory cytokine in relation to intestinal immune balance.
CBT-BR3 Bifidobacterium breve Healthy Baby O
In addition to HMO degradation function, it also has effects on metabolic syndrome and acetaldehyde decomposition function.
CBT-BF3 Bifidobacterium bifidum Healthy Baby O
A strain degrades HMO and locates as the dominant species of intestinal flora within the first 1-2 weeks of life.
CBT-BG7 Bifidobacterium longum Healthy Baby O
Degrading HMO, it also has high antiviral activity against rotavirus and inhibits the activity of H.pylori.
益生菌菌屬
Genus (Cell Type)
Coccus
菌株代號
Name
益生菌菌種
Species
來源
Origin
GRAS 特性
Characteristics
CBT-ST3 Streptococcus thermophilus Healthy Human O
It grows rapidly in the intestine and helps Lactobacillus and Bifidobacterium settle in the intestines.

LAB2PRO™益生菌各項功能性專利

骨密配方專利

KR101279852B1

CBT-ST3 CBT-LR5 CBT-LPC5

糖友配方專利

KR101228035B1

CBT-ST3 CBT-LR5 CBT-LPC5

IBS配方專利

KR101473146B1

CBT-LA1 CBT-LR5 CBT-BF3 CBT-BL3 CBT-BG7 CBT-ST3

生長壯壯專利

KR101589465B1 / KR101589467B1 /KR101589466B1

CBT-BR3 CBT-BF3 CBT-BG7 CBT-BT1

AD免調配方專利

KR101656208B1

CBT-LC5 CBT-LP3 CBT-LR5 CBT-BL3

肉肉代謝專利菌

KR101611833B1 / KR101611834B1 / KR101611837B1 / KR101611830B1 / KR101611832B1

CBT-LA1 CBT-LP3 CBT-LR5 CBT-BR3 CBT-BL3

LAB2PRO™後生元系列

Prolac-T®專利乳酸菌素(Postbiotics後生元)

熱殺處理L. acidophilus (LA1)及其二次代謝產物
三小時抑制格蘭氏陰性菌測試
三小時抑制格蘭氏陰性菌測試
不受重病及易感染者食用限制
不受高溫限制,穩定性佳
無抗生素不分好壞菌通殺的缺點
  • 只抑制殺死壞菌不殺好菌,完整提升活菌益生菌產品功效
  • 抑制或殺死壞菌種類包含:
    Staphylococcus aureus 金黃色葡萄球菌
    Micrococcus luteus 黃褐微球菌
    Bacillus cereus 蠟狀芽孢桿菌
    Salmonella typhimurium 鼠傷寒沙門氏菌
    Shigella flexneri 志賀氏菌
    Salmonella paratyphi-A 副傷寒沙門氏菌
    Escherichia coli 大腸桿菌
抑菌&製程專利:韓國、中國、歐洲
原廠文獻:
  1. 1) 抑制腸道中害菌、致病菌生長
  2. 2) 改善大腸激躁症、降血脂

Safelac™專利乳酸菌肽Bacteriocin(發酵代謝物―後生元)

P. pentosaceus發酵代謝培養液濃縮
專一性抑制效果,針對李斯特菌(Listeria monocytogenes)及幽門螺旋桿菌(Helicobacter pylori)
臨床實驗證實改善因幽門螺旋桿菌所引起之胃潰瘍和十二指腸潰瘍
無抗生素不分好壞菌通殺的缺點
不受重病及易感染者食用限制
抑制幽門螺桿菌、李斯特菌&製程專利:韓國、日本
Safelac™ 使用前後壞菌存活率(DOB 30’s value)